This report provides a thorough and comprehensive analysis of the contributions that foundations make to support research and innovation in EU Member States, Norway and Switzerland. Over the last 25 years, the role of foundations as supporters of research and innovation in Europe has grown significantly in scope and scale. However, the landscape is fragmented and, till now, largely uncharted. Little is known about the vast majority of such foundations, their activities or even their number, and information about their real impact on research and innovation in Europe was very limited. A team of national experts in the EU 27 (and Norway and Switzerland), led by VU University Amsterdam, has therefore been commissioned by the European Commission to study foundations' contribution to research and innovation in the EU under the name EUFORI. This study helps fill this knowledge gap by analysing foundations' financial contributions, and provides useful insights into the different ways they operate. It also identifies emerging trends and the potential for exploring synergies and collaboration between foundations, research-funding agencies, businesses and research institutes.